Table 2 Infection-related biomarkers and Lymphocyte subgroup of patients with COVID-19 in different clinical types.

From: Clinical characteristics and corticosteroids application of different clinical types in patients with corona virus disease 2019

 

Mild (n = 10)

General (n = 32)

Severe (n = 8)

Critical (n = 15)

P

Mean

SD

Mean

SD

Mean

SD

Mean

SD

Infection-related biomarkers

IL-6 (pg/ml)

5.36a

1.84

13.76a

9.07

15.94a

14.88

33.21

28.58

0.0003

ESR (mm/h)

8.75abc

8.66

29.38ad

21.76

33.38d

27.32

50.21cd

48.00

0.0008

Serum ferritin (ng/ml)

148.22a

196.53

396.02

260.29

469.53

188.18

1,005.16bcd

577.32

 < 0.0001

CRP (mg/l)

7.79a

10.88

12.79ac

7.70

17.84a

15.09

46.75bd

37.66

 < 0.0001

Lymphcyte subgroup

Total (n/μl)

1,810.57abc

730.95

1,266.27abd

432.62

902.5cd

441.84

512.8cd

299.52

 < 0.0001

T (n/μl)

1,194.29abc

400.10

857.74abd

283.59

582.25acd

305.80

278.27bcd

122.85

 < 0.0001

CD4 (n/μl)

685.71abc

237.23

454.16ad

193.24

317.63ad

162.30

139bcd

87.86

< 0.0001

CD8 (n/μl)

475.86ab

159.60

385.74ab

142.82

237.63cd

168.54

134.13cd

74.90

 < 0.0001

B (n/μl)

254.57ab

196.68

175.47a

100.13

127.88d

81.13

97.73cd

76.76

0.0133

NK (n/μl)

317.86a

245.90

201.23

215.58

165.88

173.58

117

137.44

0.171

  1. COVID-19 Corona Virus Disease 2019, IL-6 Interleukin-6, ESR erythrocyte sedimentation rate, CRP, C-reactive protein.
  2. aCompared to critical type, P < 0.05.
  3. bCompared to severe type, P < 0.05.
  4. cCompared to general type, P < 0.05.
  5. dCompared to mild type, P < 0.05.