Table 2 Infection-related biomarkers and Lymphocyte subgroup of patients with COVID-19 in different clinical types.
Mild (n = 10) | General (n = 32) | Severe (n = 8) | Critical (n = 15) | P | |||||
|---|---|---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | Mean | SD | Mean | SD | ||
Infection-related biomarkers | |||||||||
IL-6 (pg/ml) | 5.36a | 1.84 | 13.76a | 9.07 | 15.94a | 14.88 | 33.21 | 28.58 | 0.0003 |
ESR (mm/h) | 8.75abc | 8.66 | 29.38ad | 21.76 | 33.38d | 27.32 | 50.21cd | 48.00 | 0.0008 |
Serum ferritin (ng/ml) | 148.22a | 196.53 | 396.02 | 260.29 | 469.53 | 188.18 | 1,005.16bcd | 577.32 | < 0.0001 |
CRP (mg/l) | 7.79a | 10.88 | 12.79ac | 7.70 | 17.84a | 15.09 | 46.75bd | 37.66 | < 0.0001 |
Lymphcyte subgroup | |||||||||
Total (n/μl) | 1,810.57abc | 730.95 | 1,266.27abd | 432.62 | 902.5cd | 441.84 | 512.8cd | 299.52 | < 0.0001 |
T (n/μl) | 1,194.29abc | 400.10 | 857.74abd | 283.59 | 582.25acd | 305.80 | 278.27bcd | 122.85 | < 0.0001 |
CD4 (n/μl) | 685.71abc | 237.23 | 454.16ad | 193.24 | 317.63ad | 162.30 | 139bcd | 87.86 | < 0.0001 |
CD8 (n/μl) | 475.86ab | 159.60 | 385.74ab | 142.82 | 237.63cd | 168.54 | 134.13cd | 74.90 | < 0.0001 |
B (n/μl) | 254.57ab | 196.68 | 175.47a | 100.13 | 127.88d | 81.13 | 97.73cd | 76.76 | 0.0133 |
NK (n/μl) | 317.86a | 245.90 | 201.23 | 215.58 | 165.88 | 173.58 | 117 | 137.44 | 0.171 |