Figure 3

Effect of adoptively transferred BMDCs with or without the SOCS3 gene on lung pathology in OVA-induced asthmatic mice. (A) Protocol for OVA-mediated induction of allergic asthma and SOCS3+/+ DC or SOCS3−/− DC adoptive transfer into OVA-sensitized mice via intraperitoneal injection (DCs pulsed with LPS before transfer). (B) Representative photomicrographs of lung sections stained with H&E and examined at × 100 magnification. The same experiment was repeated 3 times with similar results (n = 6 in each group). C. The scores for lung tissue pathology. The columns and error bars represent the mean and SEM (**P < 0.01, ns: no significant difference).