Figure 4 | Scientific Reports

Figure 4

From: Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression

Figure 4

Functional characterization of myotubes. (A) Contraction traces of individual myotubes from iPSC-derived SOD1 E100G, SOD1 L144P and WT control cultures at 0.3, 0.5, 1, 2 and 4 Hz, on day 14 of myotube differentiation. Electrical pulses were elicited at 1 V for 15 s. (B, C) Bar graphs showing the percentage of contraction synchrony at days 14 and 21. p ≤ 0.05 ANOVA on ranks followed by Holm-Sidak method. NS Not significant.

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