Table 1 Comparison of the clinical and epidemiologic characteristics between mite-sensitized rhinitis and asthma, and non-mite-sensitized healthy controls.

From: Cross-talk between airway and gut microbiome links to IgE responses to house dust mites in childhood airway allergies

Characteristics

Mite-sensitized

P-value

Mite-sensitized

Non-mite-sensitized

P-value

Rhinitis (n = 20)

Asthma (n = 18)

Total (n = 38)

Controls (n = 22)

Age (yr)

4.35 ± 0.40

4.39 ± 0.53

0.848

4.37 ± 0.45

4.59 ± 0.36

0.178

Sex, male

14 (70.0%)

12 (66.7%)

0.460

26 (68.4%)

10 (45.5%)

0.266

Probiotic supplements

6 (30.0%)

10 (55.6%)

0.370

16 (42.1%)

8 (36.4%)

1.000

Cesarean delivery

6 (30.0%)

6 (33.3%)

1.000

12 (31.6%)

6 (27.3%)

1.000

Maternal atopy

6 (30.0%)

10 (55.6%)

0.524

16 (42.1%)

10 (45.5%)

0.858

Passive smoking

8 (40.0%)

10 (55.6%)

0.740

18 (47.4%)

12 (54.5%)

0.705

Household income

Low, 500,000 NTD

10 (50.0%)

9 (50.0%)

0.276

19 (50.0%)

10 (45.5%)

0.152

Medium, 500,000–1,000,000 NTD

4 (20.0%)

7 (38.9%)

11 (28.9%)

12 (54.5%)

High, > 1,000,000 NTD

6 (30.0%)

2 (11.1%)

8 (21.1%)

0 (0.0%)

Allergen-specific IgE, kU/L

D. pteronyssinus

54.58 ± 42.63

20.8 ± 34.07

0.065

38.58 ± 41.53

3.27 ± 8.69

0.021

D. farinae

38.63 ± 38.21

12.49 ± 18.64

0.095

26.25 ± 32.62

1.41 ± 3.33

0.011

Total serum IgE, kU/L

623.20 ± 632.22

164.52 ± 192.84

0.043

405.93 ± 521.29

44.92 ± 36.31

0.008

Total fecal IgE, kU/L

25.20 ± 32.45

4.63 ± 3.94

0.182

15.46 ± 25.39

1.92 ± 1.26

0.003

  1. All P-values < 0.05, which is in bold, are significant.
  2. Data shown are mean ± SD or number (%) of patients as appropriate.
  3. yr year, NTD New Taiwan Dollar, IgE immunoglobulin E.