Figure 1

Venn map and hierarchical clustering of the identified proteins. (A) Venn map of the identified proteins. (B) Gene ontology (GO) analysis of the identified proteins to AIS, MIA and LPA. (a) Biological process. 1, cellular component organization or biogenesis (GO:0071840); 2, cellular process (GO:0009987); 3, localization (GO:0051179); 4, reproduction (GO:0000003); 5, biological regulation (GO:0065007); 6, response to stimulus (GO:0050896); 7, pigmentation (GO:0043473); 8, developmental process (GO:0032502); 9, multicellular organismal process (GO:0032501); 10, rhythmic process (GO:0048511); 11, biological adhesion (GO:0022610); 12, metabolic process (GO:0008152); 13, immune system process (GO:0002376). (b) Molecular function. 1, translation regulator activity (GO:0045182); 2, transcription regulator activity (GO:0140110); 3, molecular transducer activity (GO:0060089); 4, binding (GO:0005488); 5, structural molecule activity (GO:0005198); 6, molecular function regulator (GO:0098772); 7, catalytic activity (GO:0003824); 8, transporter activity (GO:0005215). (c) Protein class. 1, extracellular matrix protein (PC00102); 2, cytoskeletal protein (PC00085); 3, transporter (PC00227); 4, transmembrane receptor regulatory/adaptor protein (PC00226); 5, transferase (PC00220); 6, oxidoreductase (PC00176); 7, lyase (PC00144); 8, cell adhesion molecule (PC00069); 9, ligase (PC00142); 10, nucleic acid binding (PC00171); 11, signaling molecule (PC00207); 12, enzyme modulator (PC00095); 13, calcium-binding protein (PC00060); 14, defense/immunity protein (PC00090); 15, hydrolase (PC00121); 16, transfer/carrier protein (PC00219); 17, membrane traffic protein (PC00150); 18, transcription factor (PC00218); 19, chaperone (PC00072); 20, cell junction protein (PC00070); 21, surfactant (PC00212); 22, structural protein (PC00211); 23, storage protein (PC00210); 24, isomerase (PC00135); 25, receptor (PC00197).