Figure 6 | Scientific Reports

Figure 6

From: Transcriptomic determinants of the response of ST-111 Pseudomonas aeruginosa AG1 to ciprofloxacin identified by a top-down systems biology approach

Figure 6

Definitive large scale network of DEGs, identification of hub genes and associated groups in PaeAG1 after treatment with ciprofloxacin. Network showing all 518 DEGs genes and their interactions (449 genes have at least one connection). Known interactions according to STRINGdb (database-based method) are shown as solid lines and data-driven interactions according to data-driven co-expression analysis as dashed lines. Enriched nodes associated to KEGG annotation are colored according to each pathway (more details in Table 3). Phages genes, virulence factors and antibiotic resistance genes are represented as triangles, arrowheads and rhomboids, respectively. Other genes are represented as ellipses.

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