Table 1 Locations of all 21 SNPs that are different between the coding regions of ECM causing PbANKA and non-ECM causing PbNK65 parasites.

From: Testing the impact of a single nucleotide polymorphism in a Plasmodium berghei ApiAP2 transcription factor on experimental cerebral malaria in mice

SNP

Gene ID

Product

Length

Position of mutation

Base in ANKA

Base in NK65

ANKA sequence

NK65 sequence

aa ANKA

aa NK65

1

PBANKA_030400

Conserved Plasmodium protein—unknown function

5,934

3,239

G

A

AGA

AAA

R

K

2

PBANKA_144660

Conserved Plasmodium protein—unknown function

3,093

2,204

T

A

ATA

AAA

I

K

3

PBANKA_0112100

Transcription factor with AP2 domain(s)

7,737

5,468

T

C

TTT

TCT

F

S

4

PBANKA_090710

Inner membrane complex protein 1b

1,608

364

A

G

ACC

GCC

T

A

5

PBANKA_122210

Regulator of chromosome condensation, putative

1,953

1,465

T

G

TAT

GAT

Y

D

6

PBANKA_134180

Conserved Plasmodium protein—unknown function

12,030

9,202

A

T

AAT

TAT

N

Y

7

PBANKA_140230

Conserved Plasmodium protein—unknown function

24,729

11,948

C

T

TGC

TAC

C

Y

8

PBANKA_141570

Transcription factor with AP2 domain(s)

7,464

7,461

G

A

ATG

ATA

M

I

9

PBANKA_083100

Merozoite surface protein 1

5,376

4,096

A

G

AGA

GGA

R

G

10

PBANKA_144610

Amino acid transporter, putative

5,313

5,070

C

A

AAG

AAT

K

N

11

PBANKA_030600

6-cysteine protein

6,864

1,852

C

A

CCA

ACA

P

T

12

PBANKA_081770

RNA-binding protein musashi, putative

1,035

611

C

T

GGA

GAA

G

E

13

PBANKA_092040

Conserved Plasmodium protein—unknown function

5,709

2,691

A

T

AAT

AAA

N

K

14

PBANKA_010160

Conserved Plasmodium protein—unknown function

2,025

462

T

A

AAT

AAA

N

K

15

PBANKA_051520

MORN repeat-containing protein 1, putative

1,095

519

A

G

ATA

ATG

I

M

16

PBANKA_080220

Serine/threonine kinase, putative

3,873

2,611

C

T

GAT

AAT

D

N

17

PBANKA_082480

RNA-binding protein, putative

600

517

G

A

CTT

TTT

L

F

18

PBANKA_143400

Phosphate translocator, putative

1,440

161

C

T

AGA

AAA

R

K

19

PBANKA_141460

Inositol polyphosphate kinase, putative

3,129

1,888

A

G

ATA

GTA

I

V

20

PBANKA_133170

Zinc finger protein, putative

2,226

1,347

A

C

AGA

AGC

R

S