Table 1 Characteristics of the Study Population.

From: Evaluation of biochemical and hematological parameters in adults with Down syndrome

 

Control

Down syndrome

p-value

n

Median (P25–P75)/n (%)

n

Median (P25-P754)/n (%)

Age (years)

84

55.0 (47.3–59.8)

248

43.0 (33.0–50.8)

 < 0.001

Male/female

84

21 (25.0)/63 (75.0)

248

132 (53.2)/116 (46.8)

 < 0.001

Arterial hypertension

84

16 (19.0)

248

3 (1.2)

 < 0.001

Dyslipidemia

84

24 (28.6)

248

37 (14.9)

0.009

Diabetes mellitus

84

6 (7.1)

248

6 (2.4)

0.082

Congenital heart disease

84

0 (0.0)

247

47 (19.0)

 < 0.001

Gastrointestinal pathology

84

1 (1.2)

247

40 (16.2)

 < 0.001

Dermatological pathology

84

2 (2.4)

247

83 (33.6)

 < 0.001

Bone pathology

84

3 (3.6)

247

36 (14.6)

0.006

Hypothyroidism

84

1 (1.2)

247

119 (48.2)

 < 0.001

Treatment for hypothyroidism

 

246

103 (41.9)

 

Hearing problems

84

0 (0.0)

245

40 (16.3)

 < 0.001

Otolaryngology pathology

84

1 (1.2)

247

37 (15.0)

 < 0.001

Ophtalmological pathology

84

1 (1.2)

246

136 (55.3)

 < 0.001

Psychiatric pathology

84

18 (21.4)

246

45 (18.3)

0.524

Epilepsy

84

1 (1.2)

247

38 (15.4)

 < 0.001

Alzheimer’s disease

84

0 (0.0)

247

50 (20.2)

 < 0.001

  1. Data are presented as frequencies (percentages) for categorical variables. Continuous variables are presented as median (interquartile range). Differences between groups were analyzed using Wilcoxon rank-sum test or Fisher's exact test.