Table 1 Characteristics of the Study Population.
From: Evaluation of biochemical and hematological parameters in adults with Down syndrome
Control | Down syndrome | p-value | |||
|---|---|---|---|---|---|
n | Median (P25–P75)/n (%) | n | Median (P25-P754)/n (%) | ||
Age (years) | 84 | 55.0 (47.3–59.8) | 248 | 43.0 (33.0–50.8) | < 0.001 |
Male/female | 84 | 21 (25.0)/63 (75.0) | 248 | 132 (53.2)/116 (46.8) | < 0.001 |
Arterial hypertension | 84 | 16 (19.0) | 248 | 3 (1.2) | < 0.001 |
Dyslipidemia | 84 | 24 (28.6) | 248 | 37 (14.9) | 0.009 |
Diabetes mellitus | 84 | 6 (7.1) | 248 | 6 (2.4) | 0.082 |
Congenital heart disease | 84 | 0 (0.0) | 247 | 47 (19.0) | < 0.001 |
Gastrointestinal pathology | 84 | 1 (1.2) | 247 | 40 (16.2) | < 0.001 |
Dermatological pathology | 84 | 2 (2.4) | 247 | 83 (33.6) | < 0.001 |
Bone pathology | 84 | 3 (3.6) | 247 | 36 (14.6) | 0.006 |
Hypothyroidism | 84 | 1 (1.2) | 247 | 119 (48.2) | < 0.001 |
Treatment for hypothyroidism | – | 246 | 103 (41.9) | ||
Hearing problems | 84 | 0 (0.0) | 245 | 40 (16.3) | < 0.001 |
Otolaryngology pathology | 84 | 1 (1.2) | 247 | 37 (15.0) | < 0.001 |
Ophtalmological pathology | 84 | 1 (1.2) | 246 | 136 (55.3) | < 0.001 |
Psychiatric pathology | 84 | 18 (21.4) | 246 | 45 (18.3) | 0.524 |
Epilepsy | 84 | 1 (1.2) | 247 | 38 (15.4) | < 0.001 |
Alzheimer’s disease | 84 | 0 (0.0) | 247 | 50 (20.2) | < 0.001 |