Table 4 Correlations between biochemical and hematological parameters and age.
From: Evaluation of biochemical and hematological parameters in adults with Down syndrome
Control | Down syndrome | |||||
|---|---|---|---|---|---|---|
n | Spearman’s rho | p-value | n | Spearman’s rho | p-value | |
Biochemical parameters | ||||||
TSH (mUI/L) | 84 | 0.186 | 0.090 | 247 | − 0.018 | 0.777 |
Na+ (mmol/L) | 84 | 0.142 | 0.197 | 248 | 0.198 | 0.002 |
K+ (mmol/L) | 83 | 0.150 | 0.175 | 245 | 0.120 | 0.060 |
Glucose (mmol/L) | 84 | 0.163 | 0.139 | 248 | 0.087 | 0.170 |
Urea (mmol/L) | 84 | 0.283 | 0.009 | 248 | 0.253 | < 0.001 |
Creatinine (µmol/L) | 84 | 0.319 | 0.003 | 248 | 0.176 | 0.005 |
eGFR (ml/min/1.73) | 84 | − 0.727 | < 0.001 | 248 | − 0.498 | < 0.001 |
Total bilirrubin (µmol/L) | 84 | − 0.006 | 0.953 | 234 | − 0.017 | 0.801 |
TG (mmol/L) | 84 | 0.023 | 0.838 | 248 | 0.150 | 0.018 |
Total cholesterol (mmol/L) | 84 | 0.265 | 0.015 | 248 | 0.269 | < 0.001 |
AST (U/L) | 84 | 0.267 | 0.014 | 245 | 0.142 | 0.026 |
ALT (U/L) | 84 | 0.158 | 0.152 | 248 | − 0.153 | 0.016 |
AF (U/L) | 78 | − 0.070 | 0.541 | 247 | 0.147 | 0.021 |
GGT (U/L) | 84 | 0.206 | 0.060 | 248 | 0.027 | 0.671 |
Total Proteins (g/L) | 84 | − 0.026 | 0.811 | 233 | − 0.066 | 0.315 |
B12 (pmol/L) | 84 | 0.150 | 0.173 | 242 | − 0.202 | 0.002 |
Folate (nmol/L) | 84 | 0.187 | 0.088 | 243 | − 0.102 | 0.113 |
Hematological parameters | ||||||
Hemoglobin (g/L) | 82 | 0.195 | 0.079 | 248 | − 0.162 | 0.011 |
Hematocrit (L/L) | 82 | 0.161 | 0.148 | 248 | − 0.129 | 0.042 |
RBC (× 1012/L) | 82 | 0.148 | 0.185 | 248 | − 0.218 | 0.001 |
MCV (fL) | 82 | − 0.022 | 0.843 | 248 | 0.291 | < 0.001 |
ESR (mm/h) | 59 | − 0.095 | 0.474 | 179 | 0.305 | < 0.001 |
MCHC (g/L) | 82 | 0.092 | 0.413 | 248 | − 0.160 | 0.011 |
MCH (pg) | 82 | 0.047 | 0.675 | 248 | 0.153 | 0.016 |
RDW (%) | 82 | − 0.003 | 0.979 | 248 | 0.172 | 0.007 |
Platelet count (× 109/L) | 81 | − 0.053 | 0.640 | 248 | − 0.235 | < 0.001 |
MPV (fL) | 82 | − 0.090 | 0.424 | 248 | 0.124 | 0.051 |
WBC (× 109/L) | 82 | − 0.089 | 0.428 | 248 | − 0.031 | 0.629 |