Figure 7

Effect of DES treatment on mutant uteri. (a) Uteri images of wild type and mutant mice with and without DES treatment. DES untreated mutant mice showed mild enlargement of uteri. (b) Haematoxylin and eosin staining of uteri sections of wild type and mutant mice with and without DES treatment. Morphology of DES treated mutant mice uteri was found to be normal. (c) Analysis of gland/stroma ratio calculated by Image J software where mutant mice without DES treatment showed significant increase in the gland/stroma ratio. Two-way Anova was used to find the statistical significance (n = 6). The values indicated by asterisk (***) differ significantly at p < 0.001.