Figure 1 | Scientific Reports

Figure 1

From: Real time monitoring of oxygen uptake of hepatocytes in a microreactor using optical microsensors

Figure 1

The figure shows details of the key components of the microreactor (bottom left). The reactor houses three channels (width 2 mm, height 600 µm) each equipped with three wells (diameter 1.5 mm, depth 300 µm). The wells (micrographs top left, scheme top right) accommodate the hepatocytes and the oxygen microsensor beads (in yellow) in a collagen matrix. The beads contain Ruthenium-Phenanthroline as dye. Its phosphorescence lifetime is a function of the oxygen concentration. Each of the nine wells can be individually addressed by the optical detection system using a computer controlled microscope stage. The scheme was created using PowerPoint for Mac (version 16.16.22, www.microsoft.com) and Adobe Photoshop CS6 for Mac (version 13.0 × 64, www.adobe.com).

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