Figure 1 | Scientific Reports

Figure 1

From: Proteins involved in the endoplasmic reticulum stress are modulated in synovitis of osteoarthritis, chronic pyrophosphate arthropathy and rheumatoid arthritis, and correlate with the histological inflammatory score

Figure 1

Histological scoring of synovial biopsies. (A) Classification of OA, CPPA and RA synovial biopsies (n = 24) according to the histological inflammatory score based on the following criteria: synovial hyperplasia (hs, 0–4), infiltration of lymphocytes (ly, 0–4), plasmocytes (pl, 0–4), polynuclear neutrophils (po, 0–3) and macrophages (CD68, 0–3). (B) Histological representation of hematoxylin eosin stained sections for synovial hyperplasia and infiltration of lymphocytes/plasmocytes and polynuclear neutrophils in one OA, CPPA or RA biopsy. (C) Immunohistochemistry using anti-CD68 antibody showing macrophage infiltration in OA, CPPA and RA synovial biopsies.

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