Table 2 IC50 of GL in DU145-DS adherent cells, DU145-DS spheres, DU145-DR adherent cells and DU145-DR spheres. DU145-DR spheres and parental cells were sensitive to GL. However, DU145-DR spheres were more sensitive to GL than DU145-DS spheres [IC50 = 6.2 μM and IC50 = 10.1 μM, respectively; p < 0.05 (*)].

From: STAT3 inhibition with galiellalactone effectively targets the prostate cancer stem-like cell population

 

GL IC50 (μM)

DU145-DS adherent cells

8.51

DU145-DS spheres

10.1

DU145-DR adherent cells

6.24

DU145-DR spheres

6.21

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