Table 1 Clinical characteristics of the patient cohort.
From: CD163+ macrophages are associated with a vulnerable plaque phenotype in human carotid plaques
Total (n = 196) | Asymptomatic (n = 93) | Symptomatic (n = 103) | p | |
|---|---|---|---|---|
Age, years | 69.3 (SD 8.4) | 67.3 (SD 6.5) | 71.2 (SD 9.5) | 0.001 |
BMI, kg/m2 | 26.7 (SD 4.1) | 26.9 (SD 4.0) | 26.6 (SD 4.2) | 0.62 |
Gender, % males | 68 (n = 133 males) | 68 (n = 63 males) | 68 (n = 70 males) | 0.97 |
Degree of stenosis, % | 90 (IQR 80–95) | 90 (IQR 80–95) | 85 (IQR 75–95) | 0.021 |
Diabetes, % | 33 (n = 65) | 25 (n = 23) | 41 (n = 42) | 0.017 |
Smoking (current), % | 34 (n = 66) | 39 (n = 36) | 29 (n = 30) | 0.16 |
Dyslipidemia, % | 95 (n = 186) | 98 (n = 91) | 92 (n = 95) | 0.12 |
Fasting lipoproteins, mmol/L | ||||
Total cholesterol | 4.4 (SD 1.1) | 4.3 (SD 1.1) | 4.4 (SD 1.2) | 0.62 |
LDL cholesterol | 2.4 (IQR 1.9–3.1) | 2.2 (IQR 1.8–3.1) | 2.6 (IQR 2.0–3.3) | 0.15 |
HDL cholesterol | 1.1 (IQR 0.9–1.3) | 1.1 (IQR 0.9–1.4) | 1.1 (IQR 0.9–1.2) | 0.72 |
Triglycerides | 1.3 (IQR 0.9–1.8) | 1.3 (IQR 0.9–1.8) | 1.2 (IQR 1.0–1.7) | 0.54 |
Hemoglobin, g/L | 141 (SD 13) | 142 (SD 13) | 140 (SD 13) | 0.15 |
eGFR | 78 (SD 28) | 82 (SD 26) | 74 (SD 29) | 0.055 |
CRP, mg/L | 3.9 (IQR 2.0–6.3) | 3.7 (IQR 1.8–5.7) | 4.0 (IQR 2.0–6.9) | 0.26 |
White blood cell count, 109/L | 7.9 (SD 1.9) | 7.9 (SD 1.9) | 8.0 (SD 2.0) | 0.72 |
Statins, % | 87 (n = 171) | 91 (n = 85) | 84 (n = 86) | 0.098 |
Anti-hypertensive treatment, % | 81 (n = 158) | 84 (n = 78) | 78 (n = 80) | 0.27 |
