Table 2 Spearman rank correlation coefficients between CD163 and plaque structural components, MMPs, and TIMPs in human carotid plaques.

From: CD163+ macrophages are associated with a vulnerable plaque phenotype in human carotid plaques

 

CD163 (% of plaque area)1

r-value

CD163 (mRNA)4

r-value

Plaque structural components

Macrophages (CD68)1

0.182*

0.27*

Smooth muscle cells (α-actin)1

 − 0.268***

 − 0.24

Elastin2

 − 0.270***

 − 0.084

Collagen2

 − 0.232**

 − 0.13

Lipids (ORO)1

0.229**

0.37**

Hemorrhage (Glycophorin A)1

0.260***

0.52***

MMPs and TIMPs

MMP-13

0.199**

0.45**

MMP-23

 − 0.157*

0.057

MMP-33

 − 0.136

0.10

MMP-93

0.224**

0.61***

MMP-103

0.160*

0.20

TIMP-13

0.453***

0.22

TIMP-23

0.059

 − 0.12

  1. 1Percentage staining of plaque area, 2Milligram per g plaque wet weight, 3Picogram per g plaque wet weight, 4counts per million read.
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