Figure 2

Core fucosylation was significantly increased in the AD patients. (A) Sera of AD patients were analyzed by AOL blot. Plates were incubated with biotin-conjugated AOL (1:15,000) or donkey anti human IgG (1 : 5,000), and staining with coomassie brilliant blue (CBB). Data were obtained in three independent experiments. (B) Densitometric analysis of the bands of IgG and AOL in AD sera. The core fucosylation levels between AD serum and health control serum were compared. The value of AOL/IgG in AD patients was analyzed. Data are shown as mean values ± SEM (*p < 0.05; **p < 0.01). (C) AOL blots with SLE sera and RA sera. Data are shown as mean values ± SEM (*p < 0.05; **p < 0.01).