Table 1 The candidate midgut proteins that interacted with P. falciparum.
Idx | ID | AA | Folds | Common name | Biological function | Category |
|---|---|---|---|---|---|---|
F3 | 006,400 | 525 | 4 | Alkaline phosphatase 2 | Alkaline phosphatase activity | Digestion |
B2 | 006,425 | 505 | 14.1 | Cyanogenic beta-glucosidase | Carbohydrate metabolic process | Digestion |
C5 | 013,078 | 414 | 10.6 | Plasma glutamate carboxypeptidase | Peptide catabolic process, proteolysis | Digestion |
D8 | 003,926 | 876 | 5 | Aminopeptidase | Digestion | |
B5 | 004,900 | 259 | 13.4 | Trypsin type 4 | Serine-type peptidase activity | Digestion |
A5 | 008,176 | 754 | 9 | Dipeptidyl-peptidase 4 | Digestion | |
A4 | 005,686 | 297 | 7.3 | Eupolytin | Digestion | |
C4 | 001,245 | 272 | 8.3 | Eupolytin | Digestion | |
H4 | 011,920 | 255 | 10.6 | Eupolytin | Digestion | |
H5 | 005,795 | 3,499 | 12.5 | Sodium-coupled monocarboxylate transporter 1 | Transmembrane transporter activity | Digestion |
C3 | 003,573 | 814 | 9.5 | Uncharacterized | Bactericidal permeability-increasing protein | Protection |
D1 | 006,268 | 94 | 6.1 | Peritrophin | Chitin metabolic process | Protection |
B8 | 002,851 | 151 | 4.2 | Niemann-Pick Type C-2 | Intracellular cholesterol transport, innate immunity | Protection |
C2 | 007,197 | 483 | 5.4 | Niemann-Pick Type C-2 | Protection | |
D2 | 001,956 | 152 | 7 | Niemann-Pick Type C-2 | Protection | |
E2 | 002,848 | 148 | 14.3 | Niemann-Pick Type C-2 | Protection | |
C7 | 011,371 | 666 | 16.1 | Tartan | Leucine-rich repeat protein | Protection |
A8 | 007,031 | 748 | 14 | FREP1 | Pathogen recognition receptor | Protection |
E8 | 004,918 | 305 | 4.3 | Fibrinogen related protein | Pathogen recognition receptor | Protection |
D3 | 013,327 | 602 | 12.4 | HPX15 | Response to oxidative stress | Protection |
E4 | 005,093 | 2,175 | 5.8 | Uncharacterized | Cadherin-like superfamily | Unknown |
C8 | 001,193 | 143 | 3.1 | Uncharacterized | CD59 Glycoprotein | Unknown |
D6 | 008,138 | 510 | 4.4 | Uncharacterized | Unknown | |
E5 | 006,972 | 113 | 25.7 | Uncharacterized | Unknown | |
G7 | 000,014 | 328 | 11.1 | Uncharacterized | Unknown |
