Figure 2

Pain and depth of invasion predict metastasis in oral cancer patients. (a) Patient reported pain is associated with metastasis (Mann–Whitney U test). Bars represent median and interquartile range. (b) Univariate analysis of metastasis predictors. Bars = 95% confidence intervals. (c) Receiver operating characteristic curve analysis was performed with pain score (n = 66 patients) and depth of invasion (n = 45 patients). (d) Pain reported by cT1N0 and cT2N0 patients (n = 36) is associated with metastasis (Mann–Whitney U test). Bars represent median and interquartile range.