Figure 4
From: Testicular blood supply is altered in the 41,XXY* Klinefelter syndrome mouse model
Contrast-enhanced ultrasound analysis of testicular blood flow in adult 40,XY* and 41,XXY* mice. (a) Perfusion of the testes by contrast agent: after injection before the contrast agent reached the testis (1). Contrast agent appears in the testicular area (2) and the covered area increases (3) until the state of maximal filling after perfusion: “floating” is reached (4). (b) Left upper and lower graph: graphical illustration of blood flow by ultrasound signal intensity in 40,XY* and 41,XXY* mice. Right upper and lower graph: after floating, the contrast agent signal was destroyed by a boost (high power ultrasound pulse) before the testes was flooded again with contrast agent (“reperfusion”). Floating as well as reperfusion duration (“time to peak”) served as the functional readout for the testicular blood flow. Green = signal measured in right; red in left testis. The red vertical line reflects the boost.
