Figure 6
Molecular docking analysis of wild type and mutant peptide of P350R with H-Ras protein. (a) Native peptide sequence (P350). (b) Superimposed image of native peptide sequence and H-Ras protein. E353 forms two H-bonds with Gly60, one H-bond with G13 and another with G15. L347 forms one H-bond with E31. (c) Mutant peptide sequence (R350). (d) Superimposed image of mutant peptide sequence with H-Ras protein. Three new H-bonds are formed with the H-Ras protein where G353 forms two H-bonds with T35, and D33. Moreover, D351 forms single H-bond with K147.
