Table 2 Univariate and multivariate logistic regression analysis of sepsis and age as death risk factors among the 1638 patients included in the study due to their discharge diagnosis of Clostridioides difficile infection (CDI).

From: Advanced age and increased CRP concentration are independent risk factors associated with Clostridioides difficile infection mortality

 

OR

95% CI

p

Association with mortality in univariate logistic regression analysis

ICD-10 code for sepsis in diagnosis at discharge

4.042

2.440–6.697

 < 0.001

Age ≥ 70 years

4.19

2.406–7.297

 < 0.001

Age ≥ 80 years

4.93

3.197–7.616

 < 0.001

Age ≥ 90 years

3.87

2.246–6.667

 < 0.001

Association with mortality in multivariate logistic regression analysis

ICD-10 code for sepsis in diagnosis on discharge

4.04

2.373–6.875

 < 0.001

Age ≥ 70 years

1.68

0.807–3.486

0.166

Age ≥ 80 years

3.34

1.858–6.016

 < 0.001

Age ≥ 90 years

1.68

0.938–3.011

 < 0.001

  1. ICD-10 International Statistical Classification of Diseases and Related Health Problems, OR odds ratio, CI confidence interval, p probability value.
  2. Sepsis was diagnosed in 119 out of 1638 persons (in 106 patients till the end of 2016 according to the older definition and in 13 since the beginning of 2017, according to the latest one). In the whole studied group, 108 persons died, 23 of them ICD -10 code for sepsis was assigned. In univariate and multivariate logistic regression analysis, the diagnosis of sepsis increased the risk of death fourfold.