Figure 2 | Scientific Reports

Figure 2

From: Metformin decreases bacterial trimethylamine production and trimethylamine N-oxide levels in db/db mice

Figure 2

Effects of an 8-week metformin treatment at a dose of 250 mg/kg on blood glucose levels in fasted and fed states (A), plasma insulin in fasted and fed states (B) and plasma lactate levels in fasted and fed states (C). The results are the mean ± SEM of 8 animals in the db/db and db/db + metformin groups and 10 animals in the db/Lean mice group. #P < 0.05 vs. db/Lean group (ANOVA, followed by Tukey’s test for A, Kruskal–Wallis test followed by Dunn’s multiple comparison test for B and C). € significantly different from the respective group at fasted state (paired t-test).

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