Table 2 DAVID-assisted shotgun proteomic analysis of key cell processes in SKOV3 and OVCAR3 cells exposed to 40 µM G28UCM using BioCarta and KEGG databases.

From: Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer

  1. For Individual Proteins: SKOV3/OVCAR3 Matching Score: 1,00: uniform regulation at the same time in both cell lines; 0,00: no uniform regulation in both cell lines at the specific time.
  2. For Key Cell Processes or Sub-Processes: Mean SKOV3/OVCAR3 Matching Score: mean of 'Individual Protein SKOV3/OVCAR3 Matching Scores'.
  3. Significantly (p < 0.05) downregulated proteins: Blue cell.
  4. Significantly (p < 0.05) upregulated proteins: Red cell.
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