Figure 3 | Scientific Reports

Figure 3

From: Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading

Figure 3

Transcutaneous immunization to protein antigen in Sbsn–/– mice. (a) OVA-specific immunoglobulins. TS, tape stripping. Trans-cutaneous immunization response was performed in mice. Any statistically differents were observed. (b) CHS response to DNFB and OX. Sbsn–/– mice show rather lower ear swelling responses to DNFB and oxazolone than did WT mice. (c) Frequency Th2 cells induced by DNFB. The frequency of IL-4+CD4+ T cells is significantly lower in Sbsn–/– mice than in WT mice.

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