Figure 6
From: 3D histopathology of human tumours by fast clearing and ultramicroscopy
3D imaging of low-grade invasive lobular adenocarcinoma of breast. (a–c) Representative 3D reconstructions of the sample recorded with × 2 and × 4 magnification, captured from different perspectives; sites of high cellular density corresponding to the invasive carcinoma are visualized as dark areas. (d) Optical section of 3D reconstruction of the sample recorded with × 4 magnification. (e) Corresponding physical section of the specimen (post-clearing), processed with standard histology, stained with H&E and recorded with × 5 magnification (see movies to Fig. 6 in Supplementary material).
