Figure 2 | Scientific Reports

Figure 2

From: APRIL-producing eosinophils are involved in gastric MALT lymphomagenesis induced by Helicobacter sp infection

Figure 2

Polarization of gastric inflammatory response in patients with gastric MALT lymphoma. (A) Relative expression of tbet, gata3 and foxp3 genes relative to the gastritis control condition. Quantification by qPCR within RNA extracted from gastric biopsies of GML (L) patients (n = 11) or gastritis (G) control population (n = 16), all infected with H. pylori. Boxed graphical representations, with the box representing 50% of values around the median (horizontal bar) and extremity segments representing extreme values, **(vs. Gastritis): p < 0.01, ***(vs. Gastritis): p < 0.001; Mann–Whitney test. (B) Example of B lymphocyte (CD20+), T lymphocyte (CD3+) and T regulatory cells (Foxp 3+, black arrows) staining within lymphoid infiltrate by IHC on sections of human gastric biopsies from GML patients.

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