Figure 4 | Scientific Reports

Figure 4

From: APRIL-producing eosinophils are involved in gastric MALT lymphomagenesis induced by Helicobacter sp infection

Figure 4

Identification of APRIL cytokine producing cells in gastric lymphoid infiltrates from patients with gastric MALT lymphoma. (A) Immunofluorescence co-labeling of the membrane form of APRIL with Stalk-1+ (magenta), CD68+ macrophages (yellow) and DAPI-labeled nuclei (blue) on sections of human gastric biopsies from GML patients. The white arrows indicate the APRIL-producing cells (Stalk-1+) and the yellow arrows the macrophages (CD68+). (B) Example of HE staining and APRIL staining (Stalk-1+) in serial sections of human gastric biopsies of GML patients. (C) Immunofluorescence co-labeling of the membrane form of the APRIL Stalk-1 (magenta), MUB40+/Siglec-8 + eosinophilic polynuclear cells (green and red) and DAPI-labeled nuclei (blue) on sections of human gastric biopsies of GML patients.

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