Table 3 Accuracy, sensitivity, specificity, positive predictive value, and negative predictive value for the six classifier models in the validation set.

From: Development of machine learning-based clinical decision support system for hepatocellular carcinoma

 

Accuracy

(%)

Sensitivity

(%)

Specificity

(%)

PPV

(%)

NPV

(%)

Classifier 1

(RFA/PEIT or resection vs. not RFA/PEIT or resection)

81.0 ± 2.6

77.4 ± 4.1

83.7 ± 3.3

77.8 ± 3.6

83.5 ± 2.5

Classifier 2

(RFA/PEIT vs. resection)

88.4 ± 3.1

56.2 ± 11.6

95.8 ± 2.7

76.8 ± 12.1

90.6 ± 2.3

Classifier 3

(TACE vs. not TACE)

76.8 ± 2.9

82.3 ± 4.1

69.3 ± 5.5

78.3 ± 4.0

74.6 ± 4.9

Classifier 4

(TACE + EBRT vs. not TACE + EBRT)

76.6 ± 4.7

43.9 ± 12.6

89.4 ± 3.9

61.6 ± 10.8

80.4 ± 4.3

Classifier 5

(Sorafenib vs. Not sorafenib)

80.0 ± 4.2

12.3 ± 13.3

95.0 ± 4.0

44.0 ± 37.7

83.1 ± 3.0

Classifier 6

(Supportive care vs. Other therapies)

80.1 ± 6.3

53.0 ± 17.6

90.4 ± 5.2

67.7 ± 15.8

83.7 ± 5.6

  1. EBRT external beam radiotherapy, NPV negative predictive value, PEIT percutaneous ethanol injection therapy, PPV positive predictive value, RFA radiofrequency ablation, TACE transarterial chemoembolisation.
  2. *Variables are presented as mean ± standard deviation.