Table 2 Receiver operating characteristic curve analysis.

From: Identification of serum IFN-α and IL-33 as novel biomarkers for type 1 autoimmune pancreatitis and IgG4-related disease

Variable

AUC

95% CI

P value

Serum IgG1

0.7917

0.626–0.958

0.1147*

Serum IgG4

0.9127

0.802–1.024

 

Serum IFN-α

0.9306

0.831–1.030

0.8149*

Serum IL-33

0.9087

0.806–1.012

0.9598*

Cut-off point

Sensitivity (%)

Specificity (%)

 

Serum IgG1 > 1054 mg/dL

71.4

75

 

Serum IgG4 > 182 mg/dL

85.7

91.7

 

Serum IFN-α > 55 pg/mL

85.7

91.7

 

Serum IL-33 > 274 pg/mL

85.7

83.3

 
  1. CI, confidence interval; AUC, area under the curve.
  2. *Statistical differences comparing serum IgG4 AUC and those for serum IgG1, IFN-α, and IL-33.
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