Figure 1
From: Preclinical efficacy of CIGB-300, an anti-CK2 peptide, on breast cancer metastasic colonization
CIGB-300 inhibits cell growth in breast cancer cells. (A) F3II, MDA-MB-231 and MCF-7 cells were treated with increasing concentrations of CIGB-300 ranging from 0 to 150 μM o for 72 h. Cell growth was determined by crystal violet colorimetric method. Each point represents the average of six independent measurements, each done in triplicate with the SEM. (B) Quantitative analyses of number of colonies per quadrant are also shown. Representative microphotographs of the effect of 7-day treatment of CIGB-300 on the colony formation assay at low density (bottom). Values represent mean ± SEM. Results are representative of three independent experiments *p < 0.05; **p < 0.01 versus control. ANOVA, Dunnett’s Multiple comparison test.
