Figure 11 | Scientific Reports

Figure 11

From: Purified Sika deer antler protein attenuates GM-induced nephrotoxicity by activating Nrf2 pathway and inhibiting NF-κB pathway

Figure 11The alternative text for this image may have been generated using AI.

Effect of different components of SDAPR on GM-induced cytotoxicity in HEK-293 cells. (A) Cells were pretreated with SDAP1 and SDAP2 (0.25, 0.5, 0.75, 1, 1.25, 1.5 mg/mL) before administration of GM (3 mg/mL) for 24 h. Data are means ± SD (n = 6). (B) Cells were pretreated with SDAPR (1, 2, 4 mg/mL), SDAP1 and SDAP2 (0.25, 0.5, 1 mg/mL) before administration of GM (3 mg/mL) for 24 h. Data are means ± SD (n = 6). **P < 0.01 as compared to the Control group. ##P < 0.01 as compared to the GM-treated group. (C) Cells were pretreated with SDAPR (4 mg/mL), SDAP1 and SDAP2 (1 mg/mL) before administration of GM (3 mg/mL) for 24 h. Data are means ± SD (n = 3). **P < 0.01 as compared to the Control group. ##P < 0.01 as compared to the GM-treated group.

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