Table 3 MBL2 diplotypes in dengue patients and healthy controls.
From: Complement protein levels and MBL2 polymorphisms are associated with dengue and disease severity
MBL2 (− 221) + Exon1 | All patients | Dengue | DWS | Healthy controls | All patients vs. healthy controls | Dengue vs. healthy controls | DWS vs. healthy controls | |||
|---|---|---|---|---|---|---|---|---|---|---|
n (%) | n (%) | n (%) | n (%) | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
Diplotypes | n = 260 | n = 158 | n = 102 | n = 161 | ||||||
XA/XA | 82 (31.5) | 52 (32.9) | 30 (29.4) | 68 (42.2) | Reference | Reference | Reference | |||
XA/XO | 59 (22.7) | 38 (24.1) | 21 (20.6) | 21 (13.0) | 3.3 (1.4–8.1) | 0.007 | 3.1 (1.0–9.3) | 0.044 | 3.7 (1.1–12.1) | 0.029 |
XA/YA | 58 (22.4) | 33 (20.9) | 25 (24.5) | 46 (28.6) | NS | NS | NS | |||
YA/XO | 35 (13.5) | 20 (12.7) | 15 (14.7) | 13 (8.1) | NS | NS | 3.8 (1–14.9) | 0.05 | ||
YA/YA | 19 (7.3) | 11 (7.0) | 8 (7.8) | 10 (6.2) | NS | NS | NS | |||
YA/YO | 3 (1.2) | 2 (1.3) | 1 (1.0) | 2 (1.2) | NS | NS | NA | |||
XO/XO | 4 (1.5) | 2 (1.3) | 2 (2.0) | 1 (0.6) | NS | NS | NS | |||
Haplotype | n = 520 | n = 316 | n = 204 | n = 322 | ||||||
XA | 281 (54.0) | 175 (55.4) | 106 (52.0) | 203 (63.0) | Reference | Reference | Reference | |||
YA | 134 (25.8) | 77 (24.4) | 57 (27.9) | 81 (25.2) | NS | NS | NS | |||
XO | 102 (19.6) | 62 (19.6) | 40 (19.6) | 36 (11.2) | 2.2 (1.2–4.2) | 0.015 | NS | 2.7 (1.2–5.9) | 0.015 | |
YO | 3 (0.6) | 2 (0.6) | 1 (0.5) | 2 (0.6) | NS | NS | NS | |||
