Figure 7

Illustration of TD and PCA application to mRNAs and miRNAs expression, respectively. TD workflow (solid line): mRNA and miRNA expression provided as matrices (middle upper) were multiplied to generate a tensor (right upper), which was converted to a matrix with summation sample suffix (lower right). The tensor was decomposed into a product of miRNA and mRNA singular value matrices (middle lower), which was converted to miRNA sample and mRNA sample singular value vectors (left). PCA workflow (broken lines): PCA directly decomposed miRNA and mRNA expression matrices into a product of PC loading attributed to samples and PC scores attributed to miRNA or mRNA.