Figure 2

Degree distribution for neurons and neural clusters. An artificial network example (a), where the yellow node has the highest degree centrality, the red node has the highest closeness centrality and the green node has the highest betweenness centrality (with solid lines and dotted lines). The node-to-node degree distribution for the network example (a) without (b) and with (c) additional dotted lines in order to mimic the connectivity phenomena observed in neural cluster networks, where the color bars present the occurrence frequency of the node-to-node matrices and the red cycles with connection pairs represent the coordinate of the peak values in the matrix. The node-to-node degree distribution for the neuronal culture networks at the start of the experiment t = 0 h (d), after 7 h (e), and the end of the experiment after 14 h (f). The node-to-node degree distribution for the neuronal culture cluster networks at the start of the experiment t = 0 h (g), after 7 h (h), and at the end of the experiment after 14 h (i).