Figure 5 | Scientific Reports

Figure 5

From: Maternal exercise conveys protection against NAFLD in the offspring via hepatic metabolic programming

Figure 5The alternative text for this image may have been generated using AI.

Effects of maternal exercise during pregnancy on offspring liver energy sensing and on AMPK signaling in early life. (A) pAMPK/AMPK protein expression. (B) PPARα protein expression. (C) pACC/ACC protein expression. (D) Pgc1α mRNA expression. (E) Cpt1a mRNA expression. (F) Acc1 mRNA expression. (G) Acc2 mRNA expression. Representative immunoblots are presented above the respective graph. Immunoblots: CO (n = 5), INT (n = 5). Uncropped images of original blots are shown in Supplementary Fig. 6. mRNA Expression: CO (n = 5), INT (n = 7). Mean ± SEM; *p < 0.05, **p < 0.01. CO control, INT intervention, P postnatal day, AMPK adenosine monophosphate-activated protein kinase, PPARα peroxisome proliferator-activated receptor alpha, ACC acetyl-CoA carboxylase, GAPDH Glycerinaldehyd-3-phosphate-dehydrogenase, Pgc1α peroxisome proliferator-activated receptor gamma coactivator 1-alpha, Cpt1a carnitine palmitoyltransferase 1A.

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