Figure 7
Influences of maternal exercise on offspring cholesterol at P21. (A) CYP7A1 protein expression [CO (n = 4), INT (n = 5)]. (B) Srebp2 mRNA expression [CO (n = 11), INT (n = 7)]. (C) Ldl-R mRNA expression [CO (n = 11), INT (n = 8)]. (D) Hmgcr mRNA expression [CO (n = 5), INT (n = 7)]. (E) SREBP1 protein expression [CO (n = 5), INT (n = 5)]. Representative immunoblots are presented above the respective graph. Uncropped images of original blots are shown in Supplementary Fig. 6. Mean ± SEM; *p < 0.05. CO control, INT intervention, Srebp sterol regulatory element-binding protein, Ldl-R LDL-Receptor, Hmgcr 3-Hydroxy-3-Methylglutaryl-CoA Reductase, CYP7A1 cholesterol 7 alpha-hydroxylase, GAPDH Glycerinaldehyd-3-phosphate-dehydrogenase.
