Table 3 Clinical and laboratory features of 8 IgAN patients with active lesions, 12 IgAN patients with chronic lesions 22 non-IgAN patients [Membranous Nephropathy (MN) n = 11, Minimal Change Disease (MCD) n = 9 and Focal Segmental Glomerulosclerosis (FSGS) n = 2] and 7 Kidney Living Donors (KLD) included in the microarray study biomarker identification.
IgAN-Active Lesions | IgAN-Chronic Lesions | Non-IgAN (MN/MCD/FSGS) | KLD | p value | ||
|---|---|---|---|---|---|---|
n | 8 | 12 | 22 | 7 | ||
Sex, male n (%) | 5 (62.5) | 9 (75.0) | 10 (45.5) | 6 (83.3) | 0.24* | |
Age, years mean (SD) | 36.62 (15.33) | 44.00 (10.72) | 47.85 (18.61) | 54.83 (13.75) | 0.176§ | |
Scr (mg/dL), mean (SD) | 1.11 (0.55) | 1.58 (0.56) | 0.92 (0.34) | 0.96 (0.14) | 0.001§ | # p = 0.001 |
eGFR-CKD/EPI [mean (SD)] | 88.58 (36.52) | 53.85 (27.63) | 92.40 (28.21) | 82.20 (4.97) | 0.004§ | # p = 0.003 |
proteinuria (g/24 h) [mean (SD)] | 2.03 (2.49) | 1.56 (1.06) | 9.10 (6.93) | n.d | < 0.001§ | #p = 0.001; &p = 0.006 |
Hypertension, n.(%) | 1 (12.5) | 4 (33.3) | 3 (13.6) | n.d | 0.51* | |
follow up years [mean (SD)] | 7.40 (2.30) | 7.36 (2.62) | 5.00 (3.66) | n.d | 0.261§ |
