Figure 2

Burden of pathogenic and likely pathogenic SNVs and CNVs in individuals with FE, GE, or PNES. Each stacked bar plot represents the total percentage of carriers of (i) pathogenic variants, highlighted in blue; (ii) likely pathogenic variants, highlighted in light blue; and (iii) variants of uncertain significance, highlighted in green. The classification of the variants in the individuals with PNES was performed for research purposes only. FE: focal epilepsy, GE: generalized epilepsy, PNES: psychogenic nonepileptic seizures, N: number of individuals with each phenotype.