Table 4 Stereological measures of the spleen.

From: Air pollution impairs recovery and tissue remodeling in a murine model of acute lung injury

Parameter

Control

PM

LPS5w

LPS + PM

LPS nebulization

PM2.5 exposure

Interaction

Spleen Volume (mm3)

53.36 ± 7.07a,b

51.65 ± 5.87a,b

68.27 ± 7.16

40.29 ± 7.52 a

n/s

p ≤ 0.0001

p ≤ 0.0001

Spleen weight per body weight ratio (mm3/g)

0.0023 ± 0.0003a,b

0.0020 ± 0.0002a

0.0029 ± 0.0003

0.0017 ± 0.0002a

n/s

p ≤ 0.0001

p ≤ 0.0001

Vv white pulp (%)

28.9 ± 4.3

30.4 ± 6.5

26.5 ± 4.9

32.3 ± 4.0

n/s

n/s

n/s

Vv red pulp (%)

66.7 ± 3.4

65.2 ± 5.6

69.9 ± 4.1

62.2 ± 3.3a

n/s

p = 0.006

n/s

Vt white pulp (mm3)

16.5 ± 3.1

16.8 ± 4.9

19.5 ± 3.6

13.7 ± 2.5

n/s

n/s

p = 0.044

Vt red pulp (mm3)

37.5 ± 5.7a,b

35.6 ± 4.1a,b

50.6 ± 6.6

26.7 ± 5.5a

n/s

p ≤ 0.0001

p ≤ 0.0001

  1. Data are expressed in mean ± standard deviation. Vv, volume density; Vt, total volume; n/s, not statistically significant. ap < 0.05 compared to the LPS5w group. bp < 0.05 compared to the LPS + PM group.
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