Table 1 Younger cohort aged 6–7 years at baseline, older cohort aged 12–13 years at baseline: Summary data on sample size, time intervals from baseline, rate of follow up, age, gender, ocular biometrics and spherical equivalent refractive error. AL, axial length, CR, corneal radius, AL/CR, axial length to corneal radius ratio, ACD, anterior chamber depth, SER, spherical equivalent refractive error, SD, standard deviation, IQR, inter-quartile range.

From: Axial growth and refractive change in white European children and young adults: predictive factors for myopia

Younger cohort

 

Baseline

Phase 2

Phase 3

Phase 4

Time from baseline (years) (IQR)

 

 + 3.00

(2.97–3.03)

 + 6.10

(5.85–6.16)

 + 9.05

(8.98–9.10)

Sample size

390

295

211

125

Rate of follow up (%)

 

76

54

32

% male

49.5

46.8

49.3

52.8

Mean age (years) ± SD

7.07 ± 0.38

10.07 ± 0.41

13.08 ± 0.35

16.01 ± 0.36

Median AL (mm) (IQR)

22.56

(22.02–23.07)

23.08

(22.53–23.59)

23.36

(22.82–23.88)

23.65

(23.12–24.26)

Median CR (mm) (IQR)

7.82

(7.63–8.00)

7.82

(7.65–8.02)

7.81

(7.68–8.04)

7.84

(7.70–8.06)

Median AL/CR ratio

(IQR)

2.89

(2.83–2.94)

2.95

(2.89–3.01)

2.98

(2.93–3.04)

3.00

(2.93–3.08)

Median ACD (mm) (IQR)

3.45

(3.33–3.59)

3.58

(3.43–3.71)

3.63

(3.49–3.78)

3.70

(3.52–3.85)

SER (D)

(IQR)

 + 1.13

(+ 0.63 to + 1.75)

 + 0.75

(+ 0.25 to + 1.25)

 + 0.75

(+ 0.25 to + 1.25)

 + 0.68

(-0.25 to + 1.13)

Older cohort

 

Baseline

Phase 2

Phase 3

Phase 4

Time from baseline (years) (IQR)

 

 + 2.97

(2.88–2.99)

 + 6.04

(+ 5.81–6.18)

 + 8.92

(8.86–9.00)

Sample size

657

427

225

113

Rate of follow up (%)

 

65

34

17

% male

50.5

45.0

43.1

36.3

Mean age (years) ± SD

13.09 ± 0.36

16.05 ± 0.32

19.20 ± 0.42

21.98 ± 0.35

Median AL (mm) (IQR)

23.30

(22.71–23.91)

23.44

(22.84–24.09)

23.47

(22.84–24.19)

23.69

(23.04–24.54)

Median CR (mm) (IQR)

7.92

(7.73–8.08)

7.93

(7.75–8.09)

7.90

(7.74–8.08)

7.98

(7.73–8.14)

Median AL/CR ratio (IQR)

2.97

(2.92–3.03)

2.98

(2.93–3.05)

3.00

(2.93–3.05)

3.01

(2.94–3.07)

Median ACD (mm)

(IQR)

3.62

(3.47–3.78)

3.67

(3.48–3.84)

3.65

(3.51–3.83)

3.68

(3.51–3.88)

SER (D)

(IQR)

 + 0.50

(+ 0.00 to + 1.13)

 + 0.50

(-0.13 to + 1.13)

 + 0.75

(-0.13 to + 1.50)

 + 0.69

(-0.25 to + 1.38)

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