Figure 6 | Scientific Reports

Figure 6

From: Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis

Figure 6

The addition of disease onset sites improves the predictive abilities of three APPs. (A) Serum sCD14 and LBP levels distinguish fast progressing patients from slowly progressing patients. The “probability cutoff” referenced in the graphic is the predicted probability of being in the fast progression group, according to the model equation, which is as follows: Probability of F vs. S = exp(− 4.618 + 5.622*[scaled(LBP) + scaled(sCD14)] + 0 (if site = A) − 1.934 (if site = L) + 1.747 (if site = B))/(1 + exp(− 0.618 + 5.622*[scaled(LBP) + scaled (sCD14)] + 0 (if site = A) − 1.934 (if site = L) + 1.747 (if site = B))). Note “Other” from this model was excluded because the data were too sparse to permit a reliable model. (B) Serum sCD14 levels, serum LBP levels, and disease onset sites distinguished fast progressing patients from slowly progressing patients.

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