Figure 9
From: Transcriptomic sex differences in sensory neuronal populations of mice
Quantitative RT-PCR validation of RNA-seq identified sex-dependent DEGs in sensory neurons. (A) Quantitative RT-PCR for 6 sex-dependent sensory neuronal DEGs. Female (F DRG) and male (M DRG) DRG sensory neurons are identified by back-tracing from hindpaw and thigh. Female (F TG) and male (M TG) TG sensory neurons are purified using Percoll gradient. Statistic is un-paired t-test (NS p > 0.05; *p < 0.05; **p < 0.01; # p < 0.0001; n = 4). Name of DEGs are indicated. Schematic of female (B) and male (C) sensory neuronal DEGs clusters that could explain difference in pain promoters in female versus male mice.
