Table 1 Highly expressing and/or regulated sex-dependent DEGs in sensory neurons.

From: Transcriptomic sex differences in sensory neuronal populations of mice

Gene ID

Female (RPKM)

Male (RPKM)

FC

Ganglia

Functional cluster

LTbR

9.4134

2.3504

6.1

DRG-per

Immune processes

Pdgfb

14.3196

4.5201

4

DRG-per

Growth factor and receptors

Ier5

12.1479

4.5225

2.7

DRG-per

Transcription

Il33

20.2942

8.0692

2.5

DRG-per

Immune processes

Vtn

39.8644

15.8489

2.5

DRG-per

Cell adhesion

Cd74

84.1816

38.4553

2.2

DRG-per

Immune processes

Tnfrsf11a

13.3066

6.4695

2.1

DRG-per

Immune processes

Tnfrsf1a

25.8606

12.3243

2.1

DRG-per

Immune processes

Notch3

19.2212

3.5448

5.5

TG-per

Transcription activator

Icam1

25.7730

7.6667

3.5

TG-per

Extracellular matrix

Cntfr

9.7744

3.3522

2.9

TG-per

Growth factor and receptors

Col1a2

55.3372

19.8403

2.8

TG-per

Extracellular matrix

Ephb6

34.2972

12.7276

2.7

TG-per

Transcription

Socs3

19.2212

7.3801

2.6

TG-per

Transcription

Cd74

101.0626

41.2613

2.5

TG-per

Immune processes

Nts

1.5979

9.6273

6.3

DRG-per

Ligand

Cbr3

5.0846

23.7600

4.2

DRG-per

Oxidation–reduction

Rpl13

9.8586

28.0830

3

DRG-per

Translation

Med27

8.5363

22.0349

2.8

DRG-per

Transcription

Ndufa8

69.0643

164.7326

2.4

DRG-per

Cellular respiration

Bud31

26.8360

87.8333

3.2

TG-per

Transcription

Cycs

2.8780

6.4099

3.0

TG-per

Oxidation–reduction

Glrx3

6.0700

16.7323

2.7

TG-per

Oxidation–reduction

Rpl15

24.2493

57.6599

2.5

TG-per

Translation

Psmd10

11.2953

25.5359

2.3

TG-per

Proteasome complex

Habp4

37.4722

9.8522

3.8

DRG-WGA

Transcription

Ajuba

16.1277

4.8867

3.3

DRG-WGA

Protein complexes

Cd74

8.0827

2.6312

3.1

DRG-WGA

Immune processes

Sox10

61.8918

19.7046

3.1

DRG-WGA

Transcription

Fbxo31

82.1134

35.7397

2.3

DRG-WGA

Proteasome complex

Fam176b

68.1104

32.7675

2.1

DRG-WGA

???

Tmem173

6.9528

27.0744

4

DRG-WGA

Immune processes

Alkal2

55.0269

139.9446

2.5

DRG-WGA

Ligand for trk receptors

Arxes2

82.6752

172.6092

2.2

DRG-WGA

Nervous system develop

Adamts8

6.0444

13.3836

2.1

DRG-WGA

Enzyme

Pkib

21.9057

47.3196

2.1

DRG-WGA

Channel regulator

  1. FC fold change; italic font shows male-selective and bold font represents female-selective DEGs. DRG-per are DRG neurons enriched by Percoll; TG-per is TG neurons enriched by Percoll; DRG-WGA are neurons innervating hindpaw skin and thigh muscle. ???—unknown functional cluster.