Table 1 Change in the proportion and cell size of fast blue-labelled trigeminal neuronal cells with or without substance P-immunoreactivity following benzalkonium chloride-induced ocular surface inflammation.

From: Ocular surface inflammation induces de novo expression of substance P in the trigeminal primary afferents with large cell bodies

 

Observed samples

Total number of FB-labelled cells

Number (%) of FB-labelled cells with SP-IR

Cell size of FB-labelled cells with SP-IR (μm2, mean ± SD)

Cell size of FB-labelled cells without SP-IR (μm2, mean ± SD)

Control

6

99

26 (26.3%)

309.1 ± 109.5

322.0 ± 89.1

BAK

6

144

70 (48.6%)*

415.6 ± 262.9†

327.2 ± 198.2

1 week

6

144

68 (47.2%)*

494.5 ± 343.8†

298.1 ± 137.1

2 months

6

72

30 (41.7%)*

518.7 ± 307.5†

311.8 ± 208.9

  1. BAK benzalkonium chloride, FB fast blue, SP-IR substance P-immunoreactivity, SD standard deviation.
  2. *Significant difference compared to the control group by Chi-square test (P < 0.05).
  3. †Significant difference compared to the control group by Dunn’s multiple comparison test as a post-hoc test of non-parametric ANOVA test (P < 0.05).
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