Figure 3 | Scientific Reports

Figure 3

From: Th17/Treg imbalance in COPD development: suppressors of cytokine signaling and signal transducers and activators of transcription proteins

Figure 3

Intracellular signaling and the Th17 response. The density of positive cells for (a) STAT3, (b) pSTAT3 and (c) IL-17 in peribronchovascular areas in the control groups after 3 (n = 9, 9 and 7, respectively) and 6 months (n = 7, 7 and 8, respectively) and in the smoke groups after 3 (n = 8, 8 and 9, respectively) and 6 months (n = 8, 8 and 7, respectively). The data are shown as the mean ± SE. The smoke groups after 6 months: (a) *p = 0.028 (t-test), (b) *p = 0.031 (t-test) and (c) *p = 0.032 (t-test) compared with their controls. (d) Representative photomicrographs of peribronchovascular areas are shown at 200 × magnification, and images at 1,000 × magnification are shown in each insert.

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