Figure 4 | Scientific Reports

Figure 4

From: Th17/Treg imbalance in COPD development: suppressors of cytokine signaling and signal transducers and activators of transcription proteins

Figure 4

Intracellular SOCS1 and SOCS3 signaling. The density of positive cells for (a) SOCS1 and (b) SOCS3 in peribronchovascular areas in the control groups after 3 (n = 8 and 8, respectively) and 6 months (n = 8 and 8, respectively) and in the smoke groups after 3 (n = 9 and 8, respectively) and 6 months (n = 6 and 7, respectively). The data are shown as the mean ± SE. The smoke groups after 3 and 6 months: (a) *p = 0.035 (t-test) and *p = 0.013 (t-test); (b) *p = 0.015 (t-test) and *p = 0.046 (t-test), respectively, compared with their controls. (c) Representative photomicrographs of peribronchovascular areas are shown at 200 × magnification, and images at 1,000 × magnification are shown in each insert.

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