Figure 3 | Scientific Reports

Figure 3

From: A computational guided, functional validation of a novel therapeutic antibody proposes Notch signaling as a clinical relevant and druggable target in glioma

Figure 3

Notch expression associates to molecular properties of gliomas. (A and B) Notch score was significantly increased in recurrent gliomas, in tumors with mutant form of IDH1 and in cases without chromosome 1p/19q co-deletion. The significance of the difference between two groups was assessed by student's t test, between three groups by one-way ANOVA. Numbers of each cases associated to molecular subtype are provided in Supplementary File S6.

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