Table 1 Patient baseline and follow up characteristics in each group.

From: Sensitivity and specificity of blood-fluid levels for oral anticoagulant-associated intracerebral haemorrhage

Characteristic

Total number n = 857

Fluid level n = 18

Non fluid level n = 839

p value

Age (years) (median, IQR)

75.5 (65.8–82.4)

79.5 (70.5–83.0)

75.5 (65.6–82.3)

0.2588

Male n, (%)*

496 (57.9%)

14 (77.8%)

482 (57.4%)

0.0957

White background n, (%)

743 (86.7%)

15 (88.2%)

728 (86.8%)

0.5657

Anticoagulants n, (%)

360 (42.0%)

15 (83.3%)

345 (41.1%)

0.0004

Comorbidities

Atrial fibrillation n, (%)

303 (35.4%)

14 (77.8%)

289 (34.4%)

0.0008

Hypertension n, (%)

566 (66.0%)

12 (66.7%)

554 (66.0%)

1.0000

History of previous stroke

IS n, (%)

118 (13.8%)

4 (25.0%)

114 (13.6%)

0.2647

ICH n, (%)

35 (4.1%)

2 (12.5%)

33 (3.9%)

0.1430

TIA n, (%)

98 (11.4%)

1 (6.7%)

97 (11.6%)

1.000

Medication on admission

Aspirin n, (%)

189 (22.1%)

1 (5.9%)

188 (22.4%)

0.1403

Warfarin n, (%)

323 (37.7%)

14 (77.8%)

309 (36.8%)

0.0008

Clinical measurements

SBP (median, IQR)

166 (147–190)

160 (140–172)

167 (147–190)

0.1475

DBP (median, IQR)

90 (79–105)

83 (78.5–91.5)

90 (79–105)

0.2745

GCS (median, IQR)

15 (14–15)

15 (14–15)

15 (14–15)

0.8221

Blood results on admission

INR (median, IQR)

1.11 (1.00–2.40)

3.05 (2.23–3.90)

1.10 (1.00–2.30)

0.0001

Management received

Surgery n, (%)

29 (3.4%)

2 (11.1%)

27 (3.2%)

0.1242

AC reversal n, (%)

269 (31.4%)

13 (72.2%)

256 (31.1%)

0.0005

Haematoma location**

   

0.0524

Lobar n, (%)

296 (34.5%)

10 (55.6%)

286 (34.1%)

 

Deep n, (%)

459 (53.6%)

5 (27.8%)

454 (54.1%)

 

Infratentorial n, (%)

79 (9.2%)

3 (16.7%)

76 (9.1%)

 

Haematoma volume (median, IQR)

7.1 (2.4–17.5)

14.1 (5.5–23.7)

7.0 (2.3–17.2)

0.0451

Intraventricular extension n, (%)

249 (29.1%)

2 (11.1%)

247 (29.4%)

0.1345

Deceased n, (%)

127 (14.8%)

3 (20.0%)

124 (14.8%)

0.7312

  1. ICH intracerebral haemorrhage, TIA transient ischemic attack, SBP systolic blood pressure, DBP diastolic blood pressure, GCS Glasgow coma scale, INR International normalized ratio, AC anticoagulant.
  2. *Note that data on sex was missing from one patient in the sample.
  3. **Note that data on hematoma location was missing from 23 patients in the sample. The differences between the groups were statistically significant (p < 0.05) for the variables shown in bold. IS: ischemic stroke.