Figure 3 | Scientific Reports

Figure 3

From: Antibodies from Sierra Leonean and Nigerian Lassa fever survivors cross-react with recombinant proteins representing Lassa viruses of divergent lineages

Figure 3

Cross-reactivity of IgG in plasma and serum from Lassa fever survivors for recombinant proteins from LASV of lineages II–IV. Binding of IgG in serum or plasma samples (1:100 dilution) from Nigerian (NG, Panels A,C,E,G; n = 40) or Sierra Leonean (SL, Panels B,D,F,H; n = 61) Lassa fever survivors quantified using ELISA coated individually with NP, linked GP, Pf-GP or Z from LASV representing lineages II–IV (LII, LIII, LIV) as indicated. Data was analyzed using Microsoft Excel (version 16.39, Microsoft, Redmond, WA) and JMP software (version 13.0.0, SAS Institute, Inc., Cary, NC). The figure was compiled using Adobe Illustrator (version 15.1.0, San Jose, CA). Green dotted lines are linear regression plots of seroreactivity of LASV lineage II antigens versus lineage III antigens. Blue dotted lines are linear regression plots of seroreactivity of lineage II LASV antigens versus lineage IV antigens.

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