Table 1 Comparison of baseline characteristics between the antifibrotic and no-antifibrotic groups of patients with idiopathic pulmonary fibrosis.
Unmatched groups | p-value | Matched groups | p-value | |||
|---|---|---|---|---|---|---|
Antifibrotic | No-antifibrotic | Antifibrotic | No-antifibrotic | |||
No. of patients | 541 | 672 | 474 | 474 | ||
Age, years | 65.5 ± 7.8 | 67.2 ± 8.1 | < 0.001 | 65.8 ± 7.8 | 65.8 ± 8.3 | 0.904 |
Male | 451 (83.4) | 544 (81.0) | 0.293 | 392 (82.7) | 393 (82.9) | > 0.999 |
BMI | 25.0 ± 3.0 | 23.8 ± 3.1 | < 0.001 | 24.8 ± 2.8 | 24.5 ± 3.0 | 0.212 |
Smoking status | 0.929 | 0.500 | ||||
Current | 68 (12.6) | 80 (11.9) | 63 (13.3) | 55 (11.6) | ||
Former | 344 (63.6) | 433 (64.4) | 298 (62.9) | 315 (66.5) | ||
Never | 129 (23.8) | 159 (23.7) | 113 (23.8) | 104 (21.9) | ||
FVC | 66.2 ± 13.7 | 70.6 ± 17.8 | < 0.001 | 67.1 ± 13.4 | 67.0 ± 16.7 | 0.923 |
DLCO | 52.9 ± 15.2 | 57.2 ± 19.3 | < 0.001 | 53.3 ± 15.2 | 53.3 ± 18.0 | 0.963 |
Charlson comorbidity index | 1.8 ± 1.0 | 1.9 ± 1.1 | 0.469 | 1.8 ± 1.0 | 1.9 ± 1.1 | 0.762 |
